What is the Entourage Effect?

Research has shown that cannabidiol, or CBD — which is a non-intoxicating cannabinoid molecule produced by cannabis — may have the potential to treat a range of health conditions, including chronic and acute pain, anxiety disorders, seizures caused by epilepsy, and symptoms of autism.

If you are one of the growing numbers of people who are looking into using CBD to treat a health condition, you may have already researched the medicinal applications and therapeutic effects of CBD. And during your research, you may have come across the term “entourage effect.”

But what is the entourage effect? And how does it benefit CBD users? Here’s what you need to know about CBD and the entourage effect.

Phytocannabinoids CBD and the Entourage Effect

The Entourage Effect - Click image to enlarge

The Entourage Effect

Cannabis contains approximately 500 botanical compounds, including:

  • Major cannabinoids (THC, which has an intoxicating effect, and non-intoxicating CBD) and more than 100 other trace cannabinoids, which are collectively called phytocannabinoids
  • More than 200 terpenes (called terpenoids when they become oxidized), such as limonene, myrcene, humulene, pinene, linalool, and beta-caryophyllene
  • Other botanical compounds, such as vitamins, minerals, protein, fiber, omega fatty acids, flavonoids, phenols, and chlorophyll

Cannabinoids interact with cannabinoid receptors that are found in your body’s endocannabinoid system (ECS). Your ECS helps your nervous, immune, endocrine and digestive systems work together to regulate sleep, mood, reproduction, immune function, pain, motor control, brain function, appetite, metabolism, cardiovascular function, body temperature, and digestive functions.

The entourage effect is a term that refers to the enhancing, synergetic effect that occurs when the full spectrum of cannabinoids, terpenes and botanical compounds that naturally occur in the cannabis plant are consumed together.

What are the benefits of the Entourage Effect?

Studies have suggested that the botanical compounds found in cannabis work better when consumed together than they do when consumed by themselves. That means that people may experience increased benefits from full-spectrum phytocannabinoid products than they would from products that isolate individual compounds.

In a letter that was published in Psychopharmacology, an international journal, Ethan B. Russo and John M. McPartland cited previous research which showed that full-spectrum cannabis extracts were “two or four times” more effective than THC alone — and in one study, caused “… 330% greater activity in mice than THC alone.” Read the entire article (PDF).

In addition to the therapeutic properties of phytocannabinoids and terpenoids, full-spectrum cannabis products also contain important nutrients that support overall health and can even be used to supplement your diet.

When all these components work together, they stimulate your endocannabinoid system which helps your body achieve optimal balance. As a result, users of full-spectrum CBD products often report that — in addition to seeing an improvement in specific health conditions — they also notice an improvement in other aspects of their physical and mental health, such as sleep, digestion or mood.

Can I get the Entourage Effect from using CBD products?

To get the maximum potential benefits from the entourage effect, you should look for full-spectrum CBD formulations that contain high concentrations of non-psychoactive phytocannabinoids combined with other active botanical compounds that naturally occur in cannabis. Using a full-spectrum CBD product may increase the therapeutic benefits and provide other nutrients that promote overall well-being.

By purchasing a full-spectrum product, you are giving yourself the best chance of getting all the “good stuff” that cannabis has to offer without the intoxicating effects.

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